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英国BMJ(四大医学刊物)主编质疑辉瑞疫苗数据造假,真实有效率仅19-29%
送交者: sherriff[★★声望品衔9★★] 于 2021-01-16 5:58 已读 1360 次 1 赞  

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英國醫學雜志(British Medical Journal,BMJ)是世界著名的四大綜合性醫學期刊之一,BMJ的副主編Peter Doshi質疑輝瑞和Moderna的新冠疫苗實驗數據造假,他的文章刊發在BMJ 的網站上。 6park.com

https://blogs.bmj.com/bmj/2021/01/04/peter-doshi-pfizer-and-modernas-95-effective-vaccines-we-need-more-details-and-the-raw-data/


Peter Doshi: Pfizer and Moderna’s “95% effective” vaccines—we need more details and the raw data

“Suspected covid-19”

All attention has focused on the dramatic efficacy results: Pfizer reported 170 PCR confirmed covid-19 cases, split 8 to 162 between vaccine and placebo groups. But these numbers were dwarfed by a category of disease called “suspected covid-19”—those with symptomatic covid-19 that were not PCR confirmed. According to FDA’s report on Pfizer’s vaccine, there were “3410 total cases of suspected, but unconfirmed covid-19 in the overall study population, 1594 occurred in the vaccine group vs. 1816 in the placebo group.”

With 20 times more suspected than confirmed cases, this category of disease cannot be ignored simply because there was no positive PCR test result. Indeed this makes it all the more urgent to understand. A rough estimate of vaccine efficacy against developing covid-19 symptoms, with or without a positive PCR test result, would be a relative risk reduction of 19% (see footnote)—far below the 50% effectiveness threshold for authorization set by regulators. Even after removing cases occurring within 7 days of vaccination (409 on Pfizer’s vaccine vs. 287 on placebo), which should include the majority of symptoms due to short-term vaccine reactogenicity, vaccine efficacy remains low: 29% (see footnote).

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